The natural product biosynthetic potential of Red Sea nudibranch microbiomes.

ABSTRACT:

Background

Antibiotic resistance is a growing problem that can be ameliorated by the discovery of novel drug candidates. Bacterial associates are often the source of pharmaceutically active natural products isolated from marine invertebrates, and thus, important targets for drug discovery. While the microbiomes of many marine organisms have been extensively studied, microbial communities from chemically-rich nudibranchs, marine invertebrates that often possess chemical defences, are relatively unknown.

Methods

We applied both culture-dependent and independent approaches to better understand the biochemical potential of microbial communities associated with nudibranchs. Gram-positive microorganisms isolated from nudibranchs collected in the Red Sea were screened for antibacte

SUBMITTER: Abdelrahman SM 

PROVIDER: S-EPMC7868072 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature