MRI radiomics features predict immuno-oncological characteristics of hepatocellular carcinoma.

ABSTRACT:

Objective

To assess the value of qualitative and quantitative MRI radiomics features for noninvasive prediction of immuno-oncologic characteristics and outcomes of hepatocellular carcinoma (HCC).

Methods

This retrospective, IRB-approved study included 48 patients with HCC (M/F 35/13, mean age 60y) who underwent hepatic resection or transplant within 4 months of abdominal MRI. Qualitative imaging traits, quantitative nontexture related and texture features were assessed in index lesions on contrast-enhanced T1-weighted and diffusion-weighted images. The association of imaging features with immunoprofiling and genomics features was assessed using binary logistic regression and correlation analyses. Binary logistic regression analysis was also employed to analyse the associatio

SUBMITTER: Hectors SJ 

PROVIDER: S-EPMC7869026 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature