Western Kenyan Anopheles gambiae showing intense permethrin resistance harbour distinct microbiota.

ABSTRACT:

Background

Insecticide resistance poses a growing challenge to malaria vector control in Kenya and around the world. Following evidence of associations between the mosquito microbiota and insecticide resistance, the microbiota of Anopheles gambiae sensu stricto (s.s.) from Tulukuyi village, Bungoma, Kenya, with differing permethrin resistance profiles were comparatively characterized.

Methods

Using the CDC bottle bioassay, 133 2-3 day-old, virgin, non-blood fed female F₁ progeny of field-caught An. gambiae s.s. were exposed to five times (107.5 µg/ml) the discriminating dose of permethrin. Post bioassay, 50 resistant and 50 susceptible mosquitoes were subsequently screened for kdr East and West mutations, and individually processed for microbial analysis using hig

SUBMITTER: Omoke D 

PROVIDER: S-EPMC7869237 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature