Protocol for a mechanistic study of mindfulness based cognitive therapy during pregnancy.

ABSTRACT:

Objective

Preventive interventions for postpartum depression (PPD) are critical for women at elevated risk of PPD. Mindfulness based cognitive therapy - perinatal depression (MBCT-PD) is a preventive intervention that has been shown to reduce risk for PPD in women with a prior history of depression. The objective of this clinical trial is to examine two potential mechanisms of action of MBCT-PD, emotion regulation and cognitive control, using behavioral and neuroimaging methods.

Method

This baseline protocol describes a randomized control trial (RCT) with two arms, MBCT-PD and treatment as usual (TAU). We plan on enrolling 74 females with a prior history of a major depressive episode, with 37 participants randomized to each arm. Participants in the MBCT-PD arm will receive M

SUBMITTER: Mackiewicz Seghete KL 

PROVIDER: S-EPMC7869507 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature