Long-term adherence to inhaled corticosteroids and asthma control in adult-onset asthma.

ABSTRACT:

Background

In short-term studies, poor adherence to inhaled corticosteroids (ICS) has been associated with worse asthma control, but the association of long-term adherence and disease control remains unclear.

Objective

To assess the relationship between 12-year adherence to ICS and asthma control in patients with adult-onset asthma.

Methods

As part of the Seinäjoki Adult Asthma Study, 181 patients with clinically confirmed new-onset adult asthma and regular ICS medication were followed-up for 12 years. Adherence (%) to ICS was assessed individually ((µg dispensed/µg prescribed)×100) during the follow-up. Asthma control was evaluated after 12 years of treatment according to the Global Initiative for Asthma 2010 guideline.

Results

Asthma was controlled in 31% and

SUBMITTER: Vahatalo I 

PROVIDER: S-EPMC7869602 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature