Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies.

ABSTRACT: Stroke is the leading cause of disability and thesecond leading cause of death worldwide. With the global population aged 65 and over growing faster than all other age groups, the incidence of stroke is also increasing. In addition, there is a shift in the overall stroke burden towards younger age groups, particularly in low and middle-income countries. Stroke in most cases is caused due to an abrupt blockage of an artery (ischemic stroke), but in some instances stroke may be caused due to bleeding into brain tissue when a blood vessel ruptures (hemorrhagic stroke). Although treatment options for stroke are still limited, with the advancement in recanalization therapy using both pharmacological and mechanical thrombolysis some progress has been made in helping patients recover from ischemi

SUBMITTER: Paul S 

PROVIDER: S-EPMC7869696 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature