Early detection of lung cancer in Czech high-risk asymptomatic individuals (ELEGANCE): A study protocol.

ABSTRACT:

Background

Lung cancer screening in high-risk population increases the proportion of patients diagnosed at a resectable stage.

Aims

To optimize the selection criteria and quality indicators for lung cancer screening by low-dose CT (LDCT) in the Czech population of high-risk individuals. To compare the influence of screening on the stage of lung cancer at the time of the diagnosis with the stage distribution in an unscreened population. To estimate the impact on life-years lost according to the stage-specific cancer survival and stage distribution in the screened population. To calculate the cost-effectiveness of the screening program.

Methods

Based on the evidence from large national trials - the National Lung Screening Trial in the USA (NLST), the NELSON study, the r

SUBMITTER: Lambert L 

PROVIDER: S-EPMC7870244 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature