Anthropometric risk factors for ovarian cancer in the NIH-AARP Diet and Health Study.

ABSTRACT:

Objective

Identifying potentially modifiable risk factors for ovarian cancer is essential for prevention because this cancer is predominantly detected at a late stage. Here, we estimated the relations of general adiposity and measures reflecting body fat distribution to the risk of epithelial ovarian cancer.

Methods

We ascertained 683 ovarian epithelial cancers (343 high-grade serous, 141 non-high grade serous) among 145,575 women, aged 50-72 years (median follow-up 12.6 years), from the National Institutes of Health-American Association of Retired Persons (NIH-AARP) Diet and Health Study. Using Cox models, we estimated confounder-adjusted hazard ratios (HRs) and 95% confidence intervals (CI) for associations of overall ovarian cancer, high-grade serous and non-high-grade se

SUBMITTER: Baumeister SE 

PROVIDER: S-EPMC7870624 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature