Efficacy of phentolamine mesylate in reducing the duration of various local anesthetics.

ABSTRACT:

Background

To evaluate changes in the effectiveness of phentolamine mesylate in combination with different local anesthetics (LAs) and vasoconstrictors. A prospective randomized double-blind study was conducted with 90 patients divided into three groups, with each group being administered one of three different LAs: lidocaine 2% 1/80,000, articaine 4% 1/200,000, and bupivacaine 0.5% 1/200,000.

Methods

We compared treatments administered to the mandible involving a LA blockade of the inferior alveolar nerve. Results were assessed by evaluating reduction in total duration of anesthesia, self-reported patient comfort using the visual analog pain scale, incidence rates of the most common adverse effects, overall patient satisfaction, and patient feedback.

Results

The diff

SUBMITTER: Gago-Garcia A 

PROVIDER: S-EPMC7871185 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature