Piloting gender-oriented colorectal cancer screening with a faecal immunochemical test: population-based registry study from Finland.

ABSTRACT:

Objective

To assess the feasibility and evaluate the performance of a relaunched colorectal cancer (CRC) screening programme with different cut-offs for men and women.

Design

Population-based registry study.

Setting

Nine municipalities in Finland which started CRC screening with faecal immunochemical test (FIT) in April 2019 with cut-off levels 70 µg Hg/g faeces for men and 25 µg Hg/g faeces for women.

Participants

Men (n=13 059) and women (n=14 669) aged 60-66 years invited to screening during the first programme year.

Outcome measures

Participation rates, positivity rates, detection rates of CRC and advanced adenoma (AA), and positive predictive values (PPV) of FIT for CRC and AA.

Results

Altogether 21 993 invitees returned stool samples. The pa

SUBMITTER: Sarkeala T 

PROVIDER: S-EPMC7871693 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature