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The Contribution of Stress and Distress to Cardiovascular Health in Adult Survivors of Childhood Cancer.


ABSTRACT:

Background

Childhood cancer survivors are at risk for cardiovascular morbidity and mortality that is not fully explained by cancer-directed therapies. We examined the contribution of emotional stress and distress to cardiac health in adult survivors of childhood cancer.

Methods

Participants included 3,267 adult survivors enrolled in the St. Jude Lifetime Cohort Study [median (range) 29.9 (18.1-64.5) years of age; 7.7 (0-24.8) years at diagnosis; 48.4% female]. Survivors completed comprehensive medical assessments and standardized measures of depression, anxiety, posttraumatic stress symptoms (PTSS), and perceived stress. Cardiovascular-related conditions included hypertension, diabetes, dyslipidemia, cardiomyopathy, dysrhythmia, myocardial infarction (severity graded 0-4), a

SUBMITTER: Lubas MM 

PROVIDER: S-EPMC7872134 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature