Blasts from the past: is morphology useful in PGT-A tested and untested frozen embryo transfers?

ABSTRACT:

Research question

Day of cryopreservation, inner cell mass (ICM) grade, trophectoderm grade and blastocyst expansion grade have been associated with differences in live birth rate in frozen embryo transfer (FET) cycles. This study sought to examine the likelihood of live birth and whether the morphological grade of the blastocyst is more or equally useful in FET cycles among preimplantation genetic testing for aneuploidies (PGT-A) tested and untested blastocysts.

Design

This was a retrospective cohort study of 6271 vitrified-warmed, autologous, single-embryo transfer cycles among patients undergoing IVF from July 2013 to December 2017 at a single, university-affiliated infertility practice. The primary outcome was live birth, calculated by generalized estimating equations.

SUBMITTER: Shear MA 

PROVIDER: S-EPMC7872471 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature