Transcriptome and translatome of CO₂ fixing acetogens under heterotrophic and autotrophic conditions.

ABSTRACT: Acetogens are anaerobic bacteria that utilise gaseous feedstocks such as carbon monoxide (CO) and carbon dioxide (CO₂) to synthesise biomass and various metabolites via the energetically efficient Wood-Ljungdahl pathway. Because of this pathway, acetogens have been considered as a novel platform to produce biochemicals from gaseous feedstocks, potentially replacing the conventional thermochemical processes. Despite their advantages, a lack of systematic understanding of the transcriptional and translational regulation in acetogens during autotrophic growth limits the rational strain design to produce the desired products. To overcome this problem, we presented RNA sequencing and ribosome profiling data of four acetogens cultivated under heterotrophic and autotrophic conditions,

SUBMITTER: Song Y 

PROVIDER: S-EPMC7873083 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature