Radiographic Imaging to Evaluate Food Passage Rate in Preterm Piglets as a Model for Preterm Infants.

ABSTRACT: Objectives and study: Gut motility in infants mature with increasing post-menstrual age and is affected by numerous hormonal, immunological and nutritional factors. However, it remains unclear how age and diet influence gut motility and its relation to feeding intolerance and gastric residuals in preterm neonates. Using preterm piglets as a model for infants, we investigated if contrast passage rate, as determined by X-ray contrast imaging, is affected by gestational age at birth, advancing postnatal age and different milk diets. Methods: Contrast passage rate was evaluated using serial abdominal X-ray imaging on postnatal day 4 and 18 in preterm and near-term piglets fed infant formula, colostrum or intact bovine milk, with or without added fortifier (total n = 140).

SUBMITTER: Kappel SS 

PROVIDER: S-EPMC7873983 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature