A validation study of the 4-variable and 8-variable kidney failure risk equation in transplant recipients in the United Kingdom.

ABSTRACT:

Background

There is emerging evidence that the 4-variable Kidney Failure Risk Equation (KFRE) can be used for risk prediction of graft failure in transplant recipients. However, geographical validation of the 4-variable KFRE in transplant patients is lacking, as is whether the more extensive 8-variable KFRE improves predictive accuracy. This study aimed to validate the 4- and 8-variable KFRE predictions of the 5-year death-censored risk of graft failure in patients in the United Kingdom.

Methods

A retrospective cohort study involved 415 transplant recipients who had their first renal transplant between 2003 and 2015 and were under follow-up at Salford Royal NHS Foundation Trust. The KFRE risk scores were calculated on variables taken 1-year post-transplant. The area under th

SUBMITTER: Ali I 

PROVIDER: S-EPMC7874608 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature