Essential oils as an effective alternative for the treatment of COVID-19: Molecular interaction analysis of protease (M^pro) with pharmacokinetics and toxicological properties.

ABSTRACT:

Background

The current health concern to the entire world is the chronic respiratory disease caused by coronavirus 2 (COVID-19). A specific treatment or proper therapy is still lacking, and the investigations from across the world for proper drug/vaccine development towards disease control are in progress. The Coronavirus replication takes place by the conversion of the polypeptide into functional protein and this occurs due to the key enzyme Main protease (M^pro). Therefore, identification of natural and effective M^pro inhibitors could be a safe and promising approach for COVID-19 control.

Methods

The present in silico study evaluates the effect of bioactive compounds found in Eucalyptus and Corymbia species essential oil on M^pro by docking.

SUBMITTER: Panikar S 

PROVIDER: S-EPMC7874929 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature