Coronary artery calcification in COVID-19 patients: an imaging biomarker for adverse clinical outcomes.

ABSTRACT:

Background

Recent studies have demonstrated a complex interplay between comorbid cardiovascular disease, COVID-19 pathophysiology, and poor clinical outcomes. Coronary artery calcification (CAC) may therefore aid in risk stratification of COVID-19 patients.

Methods

Non-contrast chest CT studies on 180 COVID-19 patients ≥ age 21 admitted from March 1, 2020 to April 27, 2020 were retrospectively reviewed by two radiologists to determine CAC scores. Following feature selection, multivariable logistic regression was utilized to evaluate the relationship between CAC scores and patient outcomes.

Results

The presence of any identified CAC was associated with intubation (AOR: 3.6, CI: 1.4-9.6) and mortality (AOR: 3.2, CI: 1.4-7.9). Severe CAC was independently associated with

SUBMITTER: Gupta YS 

PROVIDER: S-EPMC7875715 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature