Diagnostic Sequences That Distinguish M. avium Subspecies Strains.

ABSTRACT: Over a decade ago Mycobacterium avium subspecies paratuberculosis (Map) specific genes were initially identified in a whole genome context by comparing draft genome sequences of Map strain K-10 with Mycobacterium avium subspecies hominissuis (Mah) strain 104. This resulted in identification of 32 Map specific genes, not including repetitive elements, based on the two-genome comparison. The goal of this study was to define a more complete catalog of M. avium subspecies-specific genes. This is important for obtaining additional diagnostic targets for Johne's disease detection and for understanding the unique biology, evolution and niche adaptation of these organisms. There are now over 28 complete genome sequences representing th

SUBMITTER: Bannantine JP 

PROVIDER: S-EPMC7876471 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature