Association of α1-Blocker Receipt With 30-Day Mortality and Risk of Intensive Care Unit Admission Among Adults Hospitalized With Influenza or Pneumonia in Denmark.

ABSTRACT:

Importance

Alpha 1-adrenergic receptor blocking agents (α1-blockers) have been reported to have protective benefits against hyperinflammation and cytokine storm syndrome, conditions that are associated with mortality in patients with coronavirus disease 2019 and other severe respiratory tract infections. However, studies of the association of α1-blockers with outcomes among human participants with respiratory tract infections are scarce.

Objective

To examine the association between the receipt of α1-blockers and outcomes among adult patients hospitalized with influenza or pneumonia.

Design, setting, and participants

This population-based cohort study used data from Danish national registries to identify individuals 40 years and older who were hospitalized with influen

SUBMITTER: Thomsen RW 

PROVIDER: S-EPMC7876591 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature