Effect of commercially purified deoxynivalenol and zearalenone mycotoxins on microbial diversity of pig cecum contents.

ABSTRACT:

Objective

Deoxynivalenol (DON) and zearalenone (ZEN) are mycotoxins that frequently contaminate maize and grain cereals, imposing risks to the health of both humans and animals and leading to economic losses. The gut microbiome has been shown to help combat the effects of such toxins, with certain microorganisms reported to contribute significantly to the detoxification process.

Methods

We examined the cecum contents of three different dietary groups of pigs (control, as well as diets contaminated with 8 mg DON/kg feed or 0.8 mg ZEN/kg feed). Bacterial 16S rRNA gene amplicons were acquired from the cecum contents and evaluated by next-generation sequencing.

Results

A total of 2,539,288 sequences were generated with ~500 nucleotide read lengths. Firmicutes, Bacteroidet

SUBMITTER: Reddy KE 

PROVIDER: S-EPMC7876725 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature