Mitigation of deleterious phenotypes in chloroplast-engineered plants accumulating high levels of foreign proteins.

ABSTRACT:

Background

The global demand for functional proteins is extensive, diverse, and constantly increasing. Medicine, agriculture, and industrial manufacturing all rely on high-quality proteins as major active components or process additives. Historically, these demands have been met by microbial bioreactors that are expensive to operate and maintain, prone to contamination, and relatively inflexible to changing market demands. Well-established crop cultivation techniques coupled with new advancements in genetic engineering may offer a cheaper and more versatile protein production platform. Chloroplast-engineered plants, like tobacco, have the potential to produce large quantities of high-value proteins, but often result in engineered plants with mutant phenotypes. This technology needs

SUBMITTER: Schmidt JA 

PROVIDER: S-EPMC7877051 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature