Maternal glucose tolerance in pregnancy and child cognitive and behavioural problems in early and mid-childhood.

ABSTRACT:

Background

Maternal abnormal glucose tolerance during pregnancy may adversely affect offspring cognition and behaviour, but few prospective studies investigated this association at multiple points throughout childhood.

Objectives

We hypothesised that maternal abnormal glucose tolerance is associated with child cognitive and behavioural outcomes in early and mid-childhood.

Methods

We examined the associations of maternal abnormal glucose tolerance at 26-28 weeks of pregnancy with offspring cognitive and behavioural scores in 1421 children in the Project Viva pre-birth cohort. In early (mean 3.3 years) and mid-childhood (mean 7.9 years), we measured child cognition using validated instruments, the Kaufman Brief Intelligence Test, Wide Range Assessment of Memory and Lear

SUBMITTER: Xu T 

PROVIDER: S-EPMC7877074 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature