Unveiling the Structure and Reactivity of Fatty-Acid Based (Nano)materials Thanks to Efficient and Scalable ¹⁷O and ¹⁸O-Isotopic Labeling Schemes.

ABSTRACT: Fatty acids are ubiquitous in biological systems and widely used in materials science, including for the formulation of drugs and the surface-functionalization of nanoparticles. However, important questions regarding the structure and reactivity of these molecules are still to be elucidated, including their mode of binding to certain metal cations or materials surfaces. In this context, we have developed novel, efficient, user-friendly, and cost-effective synthetic protocols based on ball-milling, for the ¹⁷O and ¹⁸O isotopic labeling of two key fatty acids which are widely used in (nano)materials science, namely stearic and oleic acid. Labeled molecules were analyzed by ¹H and ¹³C solution NMR, IR spectroscopy, and mass spectrometry (ESI-TOF and

SUBMITTER: Spackova J 

PROVIDER: S-EPMC7877562 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature