Application of low-intensity pulsed therapeutic ultrasound on mesenchymal precursors does not affect their cell properties.

ABSTRACT: Ultrasound is considered a safe and non-invasive tool in regenerative medicine and has been used in the clinic for more than twenty years for applications in bone healing after the approval of the Exogen device, also known as low-intensity pulsed ultrasound (LIPUS). Beyond its effects on bone health, LIPUS has also been investigated for wound healing of soft tissues, with positive results for various cell processes including cell proliferation, migration and angiogenesis. As LIPUS has the potential to treat chronic skin wounds, we sought to evaluate the effects produced by a conventional therapeutic ultrasound device at low intensities (also considered LIPUS) on the migration capacity of mouse and human skin mesenchymal precursors (s-MPs). Cells were stimulated for 3 days (20 minutes per d

SUBMITTER: de Lucas B 

PROVIDER: S-EPMC7877602 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature