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Epidemiology of thalassemia among the hill tribe population in Thailand.


ABSTRACT:

Background

Thalassemia is a severe disease that occurs due to abnormalities in hemoglobin genes. Various genetic factors in different populations lead to different clinical manifestations of thalassemia disease, particularly among people who have a long history of migration and who have married among tribes, such as the hill tribe people in Thailand. This genetic epidemiological study aimed to estimate the prevalence of various forms of thalassemia among the six main hill tribe populations in Thailand.

Methods

A cross-sectional study was conducted to obtain information and blood specimens from school children belonging to one of the six main hill tribes in Thailand: Akha, Lau, Hmong, Yao, Karen, and Lisu. Hill tribe children who were attending grades 4-6 in 13 selected schoo

SUBMITTER: Apidechkul T 

PROVIDER: S-EPMC7877639 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature