Lactic acid-containing products for bacterial vaginosis and their impact on the vaginal microbiota: A systematic review.

ABSTRACT:

Objective

The vaginal microbiota in bacterial vaginosis (BV) typically has low abundance of lactic acid producing lactobacilli. Lactic acid has properties that may make it effective for treating BV and/or restoring an optimal lactobacillus-dominated vaginal microbiota. We conducted a systematic review to describe the effect of intravaginal lactic acid-containing products on BV cure, and their impact on vaginal microbiota composition (PROSPERO registration: CRD42018115982).

Methods

PubMed, Embase and OVID were searched from inception to November 2019 to identify eligible studies. Included studies evaluated an intravaginal lactic acid-containing product and reported BV cure using established diagnostic methods, and/or vaginal microbiota composition using molecular methods. Stu

SUBMITTER: Plummer EL 

PROVIDER: S-EPMC7877752 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature