Shedding and transmission of a live attenuated influenza A virus vaccine in pre-weaned pigs under field conditions.

ABSTRACT: Influenza A virus (IAV) is one of the most important respiratory viruses affecting pig health and vaccination is the most common strategy to control influenza infections. In this field study we assessed the onset and duration of shedding of a live attenuated influenza virus (LAIV) vaccine, its ability to transmit to non-vaccinated pigs and whether the LAIV could be aerosolized and detected in the environment. Thirty-three litters (n = 33) of a farm using the LAIV vaccine were selected for the study, a subset of them (n = 12) were left unvaccinated and a subset of piglets (n = 3) in vaccinated litters were also left unvaccinated to serve as sentinels. Selected piglets from the litters were sampled multiple days post vaccination (DPV) by collecting nasal swabs and blood, and were tested usin

SUBMITTER: Lopez Moreno G 

PROVIDER: S-EPMC7877771 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature