Relationship between serum bilirubin levels, urinary biopyrrin levels, and retinopathy in patients with diabetes.

ABSTRACT:

Objective

Previous reports have indicated that serum bilirubin levels may be associated with diabetic retinopathy. However, the detailed mechanism is not fully understood. In this study, we evaluated the relationship between the severity of diabetic retinopathy and various factors including bilirubin levels and factors influencing bilirubin metabolism.

Methods

The study participants consisted of 94 consecutive patients with diabetes mellitus admitted to Kyushu University Hospital from April 2011 to July 2012. The patients were classified into three groups: no retinopathy (NDR), simple retinopathy (SDR), and pre-proliferative or proliferative retinopathy (PDR). The relationship between the severity of retinopathy and various factors was evaluated using univariate and logistic

SUBMITTER: Kudo K 

PROVIDER: S-EPMC7877782 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature