Insufficient iodine nutrition status and the risk of pre-eclampsia: a systemic review and meta-analysis.

ABSTRACT:

Background

Although subclinical hypothyroidism in pregnancy is one of the established risk factors for pre-eclampsia, the link between iodine deficiency, the main cause of hypothyroidism, and pre-eclampsia remains uncertain. We conducted a systematic review to determine the iodine nutrition status of pregnant women with and without pre-eclampsia and the risk of pre-eclampsia due to iodine deficiency.

Methods

MEDLINE, EMBASE, Google Scholar, Scopus and Africa-Wide Information were searched up to 30th June 2020. Random-effect model meta-analysis was used to pool mean difference in urinary iodine concentration (UIC) between pre-eclamptic and normotensive controls and pool ORs and incidence rates of pre-eclampsia among women with UIC <150 µg/L.

Results

Five eligible studi

SUBMITTER: Businge CB 

PROVIDER: S-EPMC7878161 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature