Composite grading algorithm for the National Cancer Institute's Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE).

ABSTRACT:

Background

The Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events is an item library designed for eliciting patient-reported adverse events in oncology. For each adverse event, up to three individual items are scored for frequency, severity, and interference with daily activities. To align the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events with other standardized tools for adverse event assessment including the Common Terminology Criteria for Adverse Events, an algorithm for mapping individual items for any given adverse event to a single composite numerical grade was developed and tested.

Methods

A five-step process was used: (1) All 179 possible Patient-Reported Outcomes version of the Common Ter

SUBMITTER: Basch E 

PROVIDER: S-EPMC7878323 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature