Time-varying effects of 'optimized smoking treatment' on craving, negative affect and anhedonia.

ABSTRACT:

Aims

To identify when smoking cessation treatments affect craving, negative affect and anhedonia, and how these symptoms relate to abstinence, to help evaluate the effects of particular intervention components in multi-component treatments and accelerate treatment refinement.

Design

Secondary analysis of data from a two-arm randomized controlled trial.

Setting

Seven primary care clinics in Wisconsin, United States.

Participants

Adult primary care patients who smoked daily (n = 574).

Intervention and comparator

Intervention was abstinence-optimized treatment (A-OT, n = 276) comprising 3 weeks of nicotine mini-lozenges pre-target quit day (TQD), 26 weeks of combination nicotine patch and mini-lozenges post-TQD and extensive psychosocial support. The compar

SUBMITTER: Kim N 

PROVIDER: S-EPMC7878324 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature