A National Registry Study of Patient and Renal Survival in Adult Nephrotic Syndrome.

ABSTRACT:

Introduction

We aimed to determine the mortality rate, cause of death, and rate of end-stage kidney disease (ESKD) in adults with nephrotic syndrome (NS).

Methods

We conducted a national registry-based study, including all 522 adults who had a kidney biopsy for NS in Scotland in 2014-2017. We linked the Scottish Renal Registry to death certificate data. We performed survival and Cox proportional hazards analyses, accounting for competing risks of death and ESKD. We compared mortality rates with those in the age- and sex-matched general population.

Results

A total of 372 patients had primary NS; 150 had secondary NS. Over a median follow-up of 866 days, 110 patients (21%) died. In patients with primary NS, observed versus population 3-year mortality was 2.1% (95% CI 0.

SUBMITTER: Kolb A 

PROVIDER: S-EPMC7879209 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature