Population-Based Prostate Cancer Screening With Magnetic Resonance Imaging or Ultrasonography: The IP1-PROSTAGRAM Study.

ABSTRACT:

Importance

Screening for prostate cancer using prostate-specific antigen (PSA) testing can lead to problems of underdiagnosis and overdiagnosis. Short, noncontrast magnetic resonance imaging (MRI) or transrectal ultrasonography might overcome these limitations.

Objective

To compare the performance of PSA testing, MRI, and ultrasonography as screening tests for prostate cancer.

Design, setting, and participants

This prospective, population-based, blinded cohort study was conducted at 7 primary care practices and 2 imaging centers in the United Kingdom. Men 50 to 69 years of age were invited for prostate cancer screening from October 10, 2018, to May 15, 2019.

Interventions

All participants underwent screening with a PSA test, MRI (T2 weighted and diffusion), and

SUBMITTER: Eldred-Evans D 

PROVIDER: S-EPMC7879388 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature