A biphasic approach for characterizing tensile, compressive and hydraulic properties of the sclera.

ABSTRACT: Measuring the biomechanical properties of the mouse sclera is of great interest: altered scleral properties are features of many common ocular pathologies, and the mouse is a powerful tool for studying genetic factors in disease, yet the small size of the mouse eye and its thin sclera make experimental measurements in the mouse difficult. Here, a poroelastic material model is used to analyse data from unconfined compression testing of both pig and mouse sclera, and the tensile modulus, compressive modulus and permeability of the sclera are obtained at three levels of compressive strain. Values for all three properties were comparable to previously reported values measured by tests specific for each property. The repeatability of the approach was evaluated using a test-retest experimental p

SUBMITTER: Brown DM 

PROVIDER: S-EPMC7879763 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature