Variant analysis of SARS-CoV-2 genomes in the Middle East.

ABSTRACT:

Background

Coronavirus (COVID-19) was introduced into society in late 2019 and has now reached over 88 million cases and 1.9 million deaths. The Middle East has a death toll of ~80,000 and over 35000 of these are in Iran, which has over 1.2 million confirmed cases. We expect that Iranian cases caused outbreaks in the neighbouring countries and that variant mapping and phylogenetic analysis can be used to prove this. We also aim to analyse the variants of severe acute respiratory syndrome coronavirus-2 (SARS -CoV-2) to characterise the common genome variants and provide useful data in the global effort to prevent further spread of COVID-19.

Methods

The approach uses bioinformatics approaches including multiple sequence alignment, variant calling and annotation and phylogeneti

SUBMITTER: Bindayna KM 

PROVIDER: S-EPMC7880837 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature