Efficacy of continuous erythropoietin receptor activator for end-stage renal disease patients with renal anemia before and after peritoneal dialysis initiation.

ABSTRACT:

Background

Serial management of renal anemia using continuous erythropoietin receptor activator (CERA) throughout the peritoneal dialysis initiation period has rarely been reported. We investigated the efficacy and dosage of CERA treatment from pre- to post-peritoneal dialysis initiation for anemia management in patients with end-stage renal disease.

Methods

Twenty-six patients (13 men; mean age 60.9 years) who started peritoneal dialysis between April 2012 and April 2018 were investigated. Serial changes in hemoglobin levels, transferrin saturation and ferritin levels, CERA dosage, and the erythropoietin resistance index (ERI) over a 48 week period were retrospectively examined.

Results

Mean hemoglobin levels increased significantly from 10.5 g/dL at 24 weeks prior t

SUBMITTER: Fujimoto D 

PROVIDER: S-EPMC7880977 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature