SARS-CoV-2 genomic surveillance in Rondonia, Brazilian Western Amazon.

ABSTRACT: SARS-CoV-2 has spread rapidly around the world, with Brazil currently considered an epicenter of the pandemic. The Northern region has the second highest incidence coefficient, as well as the third highest mortality rate in the country. This study aimed to investigate information about the evolutionary history of epidemic spread and genetic aspects of strains isolated on the Western Amazon, in the State of Rondônia, Brazil. It was possible to detect a total of 22 mutations. Some of these alterations may possibly be related to effects on transmissibility, the fidelity of RNA replication, the ability of cancer patients to respond to infection, beyond a mutation that emerged after the introduction of SARS-CoV-2 in Rondônia. At least two events of introduction were detected, corresponding to t

SUBMITTER: Botelho-Souza LF 

PROVIDER: S-EPMC7881028 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature