Differences in Early Immunosuppressive Therapy Among Liver Retransplantation Recipients in a National Cohort.

ABSTRACT:

Background

There is no unified consensus as to the preferred immunosuppression (IS) strategy following liver retransplantation (reLT).

Methods

This was a retrospective cohort study using the United Network for Organ Sharing database. Recipient, donor, and center characteristics associated with induction use and early maintenance IS regimen were described. Multivariable Cox proportional hazards analysis evaluated induction receipt as a predictor of post-reLT survival.

Results

There were 3483 adult reLT recipients from 2002 to 2018 at 116 centers with 95.6% being performed at the same center as the initial liver transplant. Timing of reLT was associated with induction IS use and the discharge regimen (P < 0.001 for both) but not with regimens at 6- and 12-month post-reL

SUBMITTER: Mezochow AK 

PROVIDER: S-EPMC7881052 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature