Associations of body composition with incident dementia in older adults: Cardiovascular Health Study-Cognition Study.

ABSTRACT:

Introduction

A body of literature reported associations between late-life general adiposity measures (eg, body mass index) and dementia. Little is known about the association of late-life body composition with dementia risk.

Methods

We determined this association among cognitively normal participants from the Cardiovascular Health Study- Cognition Study. Body composition was assessed by dual-energy x-ray absorptiometry in 1994-1995. Dementia was ascertained at annual follow-up from 1998-1999 to 2013. Associations of body composition with incident dementia were assessed by the Fine-Gray model.

Result

Among 344 participants (mean age 78, 62.2% women), body composition was significantly different between men and women, despite similar body mass indexes (BMIs). Increased

SUBMITTER: Cui C 

PROVIDER: S-EPMC7881417 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature