Lipid profile of Mexican children with Down syndrome.

ABSTRACT:

Introduction

Down syndrome (DS) is associated with various congenital anomalies and metabolic alterations, such as dyslipidemias, that can lead to cardiovascular disease in adulthood. This study was designed to describe the lipid concentrations and the frequency of dyslipidemias in children with DS.

Materials and methods

The sample included 386 patients, 52.4% male. The study was carried out on children with DS, aged 2-18 years old, who were patients at the Mexican National Institute of Pediatrics between May 2016 and June 2017. Their height and weight were recorded, and their serum cholesterol, HDL cholesterol, and triglyceride levels were determined.

Results

Of the total patients included, 57.5% had some type of dyslipidemia, 32.6% isolated and 24.9% combined. The m

SUBMITTER: Garcia-de la Puente S 

PROVIDER: S-EPMC7881458 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature