One-stage versus two-stage revision of the infected knee arthroplasty - a randomized multicenter clinical trial study protocol.

ABSTRACT:

Background

A two-stage prosthesis exchange procedure has been the gold standard in surgical treatment of the chronically infected knee arthroplasty so far. This includes 2 surgeries/hospitalizations and an interim period of 2-3 months between surgeries with impaired health, functional status and quality of life of the patients. A one-stage exchange procedure holds many obvious advantages compared to the two-stage approach, but outcomes of a one-stage versus two-stage procedures have never been investigated in a randomized clinical trial. The purpose of this study is primarily to investigate time-adjusted differences in functional status of patients after one-stage versus two-stage revision. Secondary, to report time-adjusted differences in quality of life, complications (including

SUBMITTER: Lindberg-Larsen M 

PROVIDER: S-EPMC7881574 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature