A Network Pharmacology Study on the Molecular Mechanisms of FDY003 for Breast Cancer Treatment.

ABSTRACT: Herbal medicines have drawn considerable attention with regard to their potential applications in breast cancer (BC) treatment, a frequently diagnosed malignant disease, considering their anticancer efficacy with relatively less adverse effects. However, their mechanisms of systemic action have not been understood comprehensively. Based on network pharmacology approaches, we attempted to unveil the mechanisms of FDY003, an herbal drug comprised of Lonicera japonica Thunberg, Artemisia capillaris Thunberg, and Cordyceps militaris, against BC at a systemic level. We found that FDY003 exhibited pharmacological effects on human BC cells. Subsequently, detailed data regarding the biochemical components contained in FDY003 were obtained from comprehensive herbal medicine-rel

SUBMITTER: Lee HS 

PROVIDER: S-EPMC7881938 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature