The clinical utility of proton magnetic resonance spectroscopy in traumatic brain injury: recommendations from the ENIGMA MRS working group.

ABSTRACT: Proton (¹H) magnetic resonance spectroscopy provides a non-invasive and quantitative measure of brain metabolites. Traumatic brain injury impacts cerebral metabolism and a number of research groups have successfully used this technique as a biomarker of injury and/or outcome in both pediatric and adult TBI populations. However, this technique is underutilized, with studies being performed primarily at centers with access to MR research support. In this paper we present a technical introduction to the acquisition and analysis of in vivo ¹H magnetic resonance spectroscopy and review ¹H magnetic resonance spectroscopy findings in different injury populations. In addition, we propose a basic ¹H magnetic resonance spectroscopy data acquisition scheme

SUBMITTER: Bartnik-Olson BL 

PROVIDER: S-EPMC7882010 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature