Ontology highlight
ABSTRACT:
SUBMITTER: Lamers MM
PROVIDER: S-EPMC7883112 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Lamers Mart M MM van der Vaart Jelte J Knoops Kèvin K Riesebosch Samra S Breugem Tim I TI Mykytyn Anna Z AZ Beumer Joep J Schipper Debby D Bezstarosti Karel K Koopman Charlotte D CD Groen Nathalie N Ravelli Raimond B G RBG Duimel Hans Q HQ Demmers Jeroen A A JAA Verjans Georges M G M GMGM Koopmans Marion P G MPG Muraro Mauro J MJ Peters Peter J PJ Clevers Hans H Haagmans Bart L BL
The EMBO journal 20210111 5
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which may result in acute respiratory distress syndrome (ARDS), multiorgan failure, and death. The alveolar epithelium is a major target of the virus, but representative models to study virus host interactions in more detail are currently lacking. Here, we describe a human 2D air-liquid interface culture system which was characterized by confocal and electron microscopy and single-cell mRNA e ...[more]