Maternal lipid levels in pregnant women without complications in developing risk of large for gestational age newborns: a study of meta-analysis.

ABSTRACT: Background: Circulating into foetal circulation across the placental barrier, abnormal maternal serum lipids predispose neonates to metabolic dysfunction and thereafter affect the steroid metabolism and functions of extra-embryonic foetal tissues. Methods: A systematic review was conducted by searching PubMed-MEDLINE and the Cochrane library between January 2010 and January 2020. The included studies were English case control studies that described original data on at least one raw lipid measurement during pregnancy in healthy women who delivered large for gestational age (LGA) newborns and in healthy women with non-LGA newborns. The data extracted from 12 studies were pooled, and the weighted mean difference (WMD) in lipid levels was calculated using random effects models. A

SUBMITTER: Mahindra MP 

PROVIDER: S-EPMC7883316 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature