Assessing Biodegradability of Chemical Compounds from Microbial Community Growth Using Flow Cytometry.

ABSTRACT: Compound biodegradability tests with natural microbial communities form an important keystone in the ecological assessment of chemicals. However, biodegradability tests are frequently limited by a singular focus either on the chemical and potential transformation products or on the individual microbial species degrading the compound. Here, we investigated a methodology to simultaneously analyze community compositional changes and biomass growth on dosed test compound from flow cytometry (FCM) data coupled to machine-learned cell type recognition. We quantified the growth of freshwater microbial communities on a range of carbon dosages of three readily biodegradable reference compounds, phenol, 1-octanol, and benzoate, in comparison to three fragrances, methyl jasmonate, myrcene, and musk x

SUBMITTER: Ozel Duygan BD 

PROVIDER: S-EPMC7883543 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature