Evaluating the association of preoperative parecoxib with acute pain trajectories after video-assisted thoracoscopic surgery: a single-centre cohort study in Taiwan.

ABSTRACT:

Objective

The efficacy of parecoxib as pre-emptive analgesia still remains controversial. This study aimed to investigate how pre-emptive analgesia with parecoxib affected postoperative pain trajectories over time in patients undergoing thoracic surgery.

Design

Retrospective cohort study.

Setting

A single medical centre in Taiwan.

Participants

We collected 515 patients undergoing video-assisted thoracoscopic surgery at a tertiary medical centre between September 2016 and August 2017.

Interventions

Pre-emptive parecoxib before surgery.

Primary and secondary outcome measures

Daily numeric rating pain scores in the first postoperative week.

Results

A total of 196 (38.1%) of the recruited patients received parecoxib preoperatively. The latent c

SUBMITTER: Ling YH 

PROVIDER: S-EPMC7883868 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature