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Fluorophore-Appendant 5,5'-Bicalixarene Scaffolds for Host-Guest Sensing of Nitric Oxide.

ABSTRACT: Conjugated 5,5'-Bicalixarene scaffolds having fluorophores at the chain termini have been prepared and tested in the supramolecular detection of nitric oxide. Scaffolds bearing electron-rich fluorophores demonstrated a stronger turn-off response to the presence of NO than the fluorophore-free analogue in both organic and aqueous media, while no fluorescence quenching happened when the electron-deficient fluorophores were employed. Unprecedented ratiometric supramolecular sensing was observed when fluorophores of the opposite electronic demands were placed at the scaffold's termini.

SUBMITTER: Baheti A

PROVIDER: S-EPMC7884005 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Fluorophore-Appendant 5,5'-Bicalixarene Scaffolds for Host-Guest Sensing of Nitric Oxide.

Baheti Abhishek A Dobrovetsky Roman R Vigalok Arkadi A

Organic letters 20201207 24

Conjugated 5,5'-Bicalixarene scaffolds having fluorophores at the chain termini have been prepared and tested in the supramolecular detection of nitric oxide. Scaffolds bearing electron-rich fluorophores demonstrated a stronger turn-off response to the presence of NO than the fluorophore-free analogue in both organic and aqueous media, while no fluorescence quenching happened when the electron-deficient fluorophores were employed. Unprecedented ratiometric supramolecular sensing was observed whe ...[more]

PMID: 33285065

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