Quantitative Fundus Autofluorescence in the Developing and Maturing Healthy Eye.

ABSTRACT:

Purpose

Quantitative fundus autofluorescence (QAF) enables comparisons of autofluorescence intensities among participants. While clinical QAF reports mostly focused on the healthy and diseased adult retina, only very limited data of QAF in the maturing eye are available. Here, we report QAF in a large cohort of healthy children.

Methods

In this prospective monocentric cross-sectional study, 70 healthy Caucasian children (5-18 years) were multimodal imaged, including QAF and spectral domain optical coherence tomography. QAF and retinal thicknesses were measured at predefined locations (along horizontal meridian; Early Treatment Diabetic Retinopathy Study [ETDRS] grid) and correlated using custom written Fiji plugins. Standard retinae for different age groups were generated.

SUBMITTER: Probster C 

PROVIDER: S-EPMC7884289 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature