Gut Microbiota Profile in Pediatric Patients With Inflammatory Bowel Disease: A Systematic Review.

ABSTRACT: Background and Aim: Accumulating evidence have implicated gut microbiota alterations in pediatric and adult patients with inflammatory bowel disease (IBD); however, the results of different studies are often inconsistent and even contradictory. It is believed that early changes in new-onset and treatment-naïve pediatric patients are more informative. We performed a systematic review to investigate the gut microbiota profiles in pediatric IBD and identify specific microbiota biomarkers associated with this disorder. Methods: Electronic databases were searched from inception to 31 July 2020 for studies that observed gut microbiota alterations in pediatric patients with IBD. Study quality was assessed using the Newcastle-Ottawa scale. Results: A total of 41 original studi

SUBMITTER: Zhuang X 

PROVIDER: S-EPMC7884334 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature